P600 REGULATES SPINDLE ORIENTATION IN APICAL NEURAL PROGENITORS AND CONTRIBUTES TO NEUROGENESIS IN THE DEVELOPING NEOCORTEX

p600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex

Apical neural progenitors (aNPs) drive neurogenesis by means of a program consisting of self-proliferative and neurogenic divisions.The balance between these two manners of division sustains the pool of apical progenitors into late neurogenesis, thereby ensuring their availability to populate the brain with terminal cell types.Using knockout and in

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NTRK Gene Expression in Non-Small-Cell Lung Cancer

Background/Objectives: Since the discovery of oncogenic neurotrophic receptor tyrosine kinase (NTRK) gene fusions in colorectal cancer in 1986, their understanding has evolved, particularly in non-small-cell lung cancer (NSCLC) over the past five years.NTRK rearrangements, involving NTRK1, NTRK2, and NTRK3, drive tumorigenesis and have been identif

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Investigation and sequence analysis of avian polyomavirus and psittacine beak and feather disease virus from companion birds in eastern Turkey

Avian polyomavirus (APV) and psittacine beak and south park fitted hat feather disease virus (PBFDV) induce contagious and persistent diseases that affect the beaks, feathers, and immune systems of companion birds.APV causes hepatitis, ascites, hydropericardium, depression, feather disorders, abdominal distension, and potentially death.PBFDV can ka

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